Triethylamine → HCID 57513609, compound

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2-Amino-N-(benzyl-4-phenyl-thiazol-2-yl)-2-methyl-propionamide (100 mg, 0.3 mmol), 4-Fluoro-benzensulfonyl chloride (80 mg, 0.4 mmol) and triethyl amine (85 μL, 1 mmol) were stirred a solution in DMF (5 mL). Purification via HPLC afforded the title compound. 1H NMR (400 MHz, DMSO-D6) δ 1.31 (s, 6H) 4.21 (s, 2H) 7.20-7.26 (m, 3H) 7.28-7.39 (m, 5H) 7.45 (s, 2H) 7.62 (d, J=7.07 Hz, 2H) 7.85 (s, 2H) 7.95 (s, 1H) 11.80 (s, 1H). m/z 510.1 (MH+).

Provenance & Evidence