Water → HCID 67356496, compound

HRID 2368658Notes

Reaction equation

HRID 2368658 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]([NH:9][CH3:10])[C:6]([N+:11]([O-:13])=[O:12])=[CH:5][CH:4]=1.[Br-:14].[Br-].[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C([N+](CCCC)(CCCC)CCCC)CCC.C([N+](CCCC)(CCCC)CCCC)CCC.O>ClCCl.CO>[Br:14][C:4]1[CH:5]=[C:6]([N+:11]([O-:13])=[O:12])[C:7]([NH:9][CH3:10])=[N:8][C:3]=1[O:2][CH3:1]

Participants

6

Reactant 3

HCID 962WaterHCID 30239146-Methoxy-N-methyl-3-nitropyridin-2-amineHCID 23500184Tetra-n-butylammonium tribromide

Product 1

HCID 67356496HCID 67356496, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6344DichloromethaneSolvent

Procedure

6-Methoxy-N-methyl-3-nitropyridin-2-amine (7 g, 38 mmol) in 150 mL dichloromethane and 50 mL methanol were combined with tetrabutylammonium-tri-bromide (20.3 g, 42.0 mmol). The mixture was stirred at ambient temperator for 2 h. The mixture was poured into water, filtered and washed with water and ethanol and reacted without further purification.

Workup

  1. filtrationfiltered
  2. washwashed with water and ethanol
  3. customreacted without further purification

Sources & evidence

ORD record
ord-436a11e915e64a41a93834cd0d9ebeac
Source dataset
uspto-grants-2014_04
Patent number
US08703796B2

Reaction notes

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