HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → 2-Hydrazinyl-4-isopropyl-1,8-naphthyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 2-Chloro-4-isopropyl-1,8-naphthyridine | HCID 86669287 | — |
| Product | 2-Hydrazinyl-4-isopropyl-1,8-naphthyridine | HCID 67083037 | 92% |
Reaction Steps
A solution of chloro-4-isopropyl-1,8-naphthyridine (690 mg, 3.4 mmol) in NH2NH2 was reacted as outlined in Scheme 1 above to give the desired title compound (620 mg, 92%). Spectroscopic data: 1H NMR (300 MHz, CDCl3) δ ppm 1.35 (d, J=6.74 Hz, 6 H) 3.45-3.59 (m, 1 H) 6.70 (br. s., 1 H) 7.21 (dd, J=8.06, 4.54 Hz, 1 H) 8.19 (d, J=7.62 Hz, 1H) 8.79 (br. s., 1 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703797B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-df54d732f319430f9e3f00f93a472e26 |
| Source note | uspto-grants-2014_04 |