HCID 86607504, compound → HCID 67234035, compound

HRID 2368712Notes

Reaction equation

HRID 2368712 reaction equation
[CH2:1]([O:5][C:6]([C:8]1[C:9]([OH:26])=[C:10]2[CH:17]=[C:16]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=3)[S:15][C:11]2=[C:12](Cl)[N:13]=1)=[O:7])[CH2:2][CH2:3][CH3:4].C(OC(C1N=C(Cl)C2C=C(C3C=CC(OC)=CC=3)SC=2C=1O)=O)CCC>>[CH2:1]([O:5][C:6]([C:8]1[C:9]([OH:26])=[C:10]2[CH:17]=[C:16]([C:18]3[CH:19]=[CH:20][C:21]([O:24][CH3:25])=[CH:22][CH:23]=3)[S:15][C:11]2=[CH:12][N:13]=1)=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 86607504HCID 86607504, compoundHCID 86607505HCID 86607505, compound

Product 1

HCID 67234035HCID 67234035, compound

Procedure

The title compound was prepared from a mixture of 7-chloro-4-hydroxy-2-(4-methoxy-phenyl)-thieno[2,3-c]pyridine-5-carboxylic acid butyl ester and 4-chloro-7-hydroxy-2-(4-methoxy-phenyl)-thieno[3,2-c]pyridine-6-carboxylic acid butyl ester, example 3-c, analogously to experimental conditions for example 1-g; with isolation of the lower Rf isomer. MS: (+) m/z 358.05 (M+1).

Sources & evidence

ORD record
ord-4a72c86d0b3e4d1e91c0c9c825876604
Source dataset
uspto-grants-2014_04
Patent number
US08703795B2

Reaction notes

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