Sodium borohydride → HCID 12536095, compound

HRID 236892Notes

Reaction equation

HRID 236892 reaction equation
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4](=[O:11])[CH:3]=[C:2]1[CH:12]=[O:13].[BH4-].[Na+]>CO>[OH:13][CH2:12][C:2]1[O:1][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4](=[O:11])[CH:3]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 104196624-oxo-4H-chromene-2-carbaldehyde

Product 1

HCID 12536095HCID 12536095, compoundYield 55%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 4H-1-benzopyran-4-one-2-carboxaldehyde (400 mg, 0.0023 m) and sodium borohydride (8.8 mg. 0.0023 m) in methanol (20 ml) was stirred at room temperature for 30 minutes. The solvent was removed at reduced pressure to give a white solid. The solid was washed with water, sucked dry, and recrystallized from ethanol to give white crystals (220 mg, 55%), m.p. 165°-167°.

Workup

  1. customThe solvent was removed at reduced pressure
  2. customto give a white solid
  3. washThe solid was washed with water
  4. customsucked dry
  5. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-8d43d417ab5b4b19b0f78661905787b3
Source dataset
uspto-grants-1979_06
Patent number
US04158663

Reaction notes

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