HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Dimethyl 4-[4-(2-benzoxazolyl)benzyloxy]-benzylidenemalonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Dimethyl ((4-hydroxyphenyl)methylene)malonate | HCID 103565 | — |
| Reactant | p-(Benzoxazoyl)benzyl Chloride | HCID 14074166 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | Dimethyl 4-[4-(2-benzoxazolyl)benzyloxy]-benzylidenemalonate | HCID 21315311 | 41% |
Reaction Steps
A mixture of 0.1 mole 2-(4-chloromethylphenyl)benzoxazole (C) and 0.1 mole dimethyl 4-hydroxybenzylidenemalonate (D) in 300 ml. 2-butanone containing 100 g. potassium carbonate was refluxed for 18 hours and poured onto 1,000 g. ice/water. Filtration, washing with water and recrystallization from methyl cellosolve/isopropyl alcohol gave a 41% yield of the light tan crystalline product II. ##STR5##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04158658 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-0004f4c6a69043b6a1eaa88371587667 |
| Source note | uspto-grants-1979_06 |