反应详情

N-(5-Methyl-1,3,4-thiadiazol-2-yl)-benzylamine (15 g, 0.073 mole) in pyridine (200 ml) was refluxed with phenylacetyl chloride for 6 hours. The pyridine was removed under educed pressure and the residue treated with water and extracted with ether. The ethereal solution was dried, filtered and evaporated to dryness and the residue recrystallised from ethanol to give the title compound, m.p. 128° C.

1. customThe pyridine was removed
2. additionthe residue treated with water
3. extractionextracted with ether
4. customThe ethereal solution was dried
5. filtrationfiltered
6. customevaporated to dryness
7. customthe residue recrystallised from ethanol