Hydrazine → HCID 68656452, compound

Participants

Reaction Steps

Another method used for preparing examples of the invention is shown as Example 60. 4,4,4-Trifluoro-1-[5-(3-methanesulfonyl-phenyl)-thiophen-2-yl]-butane-1,3-dione was condensed directly with hydrazine to form pyrazole 3-[5-(3-Methanesulfonyl-phenyl)-thiophen-2-yl]-5-trifluoromethyl-1H-pyrazole. Alkylation of a pyrazole such as 3-[5-(3-Methanesulfonyl-phenyl)-thiophen-2-yl]-5-trifluoromethyl-1H-pyrazole could result in a mixture of positional isomers which could be separated by one skilled in the art

Provenance & Evidence