Ethanol → HCID 72683169, compound

Participants

Reaction Conditions

Reaction Steps

Water (115 mL) and 35.5 g (0.63 mol) of potassium hydroxide were added to a solution of 77 g (0.25 mol) of 3,7,11,15-tetramethylhexadec-2-ene-1-nitrile in ethanol (345 mL). The solution was stirred for 18 hours at 80° C. The reaction mixture was concentrated, and neutralized with 3M hydrochloric acid, and then extracted with ethyl acetate. The extract was washed with saturated brine, and dried over sodium sulfate. After filtration, the filtrate was concentrated to obtain 88 g of 4,8,12,16-tetramethylheptadec-3-enoic acid as a crude product.

Provenance & Evidence