Iodoethane → HCID 71574639, compound

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Reaction Steps

This compound was prepared from dimethyl 3-methyl-6,11-dihydro-5H-indolizino[6,7-b]indole-1,2-dicarboxylate (5.1 g, 15 mmol), NaH (0.54 g, 22.5 mmol) and iodoethane (2.3 g, 15 mmol). Yield 5.1 g (92%); mp 202-203° C. 1H NMR (DMSO-d6) δ 1.29 (3H, t, J=6.9 Hz, Me), 2.46 (3H, s, Me), 3.73 (3H, s, COOMe), 3.74 (3H, s, COOMe), 4.17 (2H, s, CH2), 4.20 (2H, q, J=6.9 Hz, CH2), 5.29 (2H, s, CH2), 7.05-7.09 (1H, m, ArH), 7.16-7.20 (1H, m, ArH), 7.49-7.51 (1H, m, ArH), 7.53-7.55 (1H, m, ArH). Anal. Calcd for (C21H22N2O4): C, 68.84; H, 6.05; N, 7.65. Found: C, 68.46; H, 6.06; N, 7.59.

Provenance & Evidence