関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Formamide | HCID 713 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Ethyl 2-amino-4,5-dimethyl3-thenoate | HCID 78536 | — |
| 生成物 | HCID 178435036 | HCID 178435036 | 85% |
反応手順
The mixture of ethyl 2-amino-4,5-dimethylthiophene-3-carboxylate (30 g, 0.15 mol) in 150 mL of formamide was heated at 180° C. for 4 h and cooled down. The mixture was poured into 200 mL of water and filtered. The solid was collected and recrystallized from ethanol to afford 5,6-dimethylthieno[2,3-d]pyrimidin-4-ol as yellow solid (23 g, 85%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08703941B2 |
|---|
| 出典データセット | uspto-grants-2014_04 |
|---|
| ORD ID | ord-6ac43abb6a9f400a853da38c24f673a9 |
|---|
| 出典メモ | uspto-grants-2014_04 |
|---|
