反应详情

4-Chloro-3,5-dinitrobenzoic acid (25.0 gm.) is dissolved in a cooled solution of methanol (125 ml.) and concentrated sulfuric acid (3.0 ml.). The reaction mixture is allowed to warm to room temperature and then heated to reflux for 18 hours. The product precipitated as light yellow needles on cooling, which are collected by filtration and washed with 15 ml. of methanol (24.0 gm., m.p. 102°-104.5°). Recrystallization from methanol gives light yellow needles (23.6 g., m.p. 104- 105.5). 89% yield).

1. temperatureheated
2. temperatureto reflux for 18 hours
3. customThe product precipitated as light yellow needles
4. temperatureon cooling
5. filtrationwhich are collected by filtration
6. washwashed with 15 ml
7. customRecrystallization from methanol
8. customgives light yellow needles (23.6 g., m.p. 104- 105.5)