反应详情

Potassium hydroxide (5 mL, 2 M) was added to a solution of 4-trimethysilylethynyl-N,N-dibutylaniline (3 g, 9.1 mmol) in MeOH (100 mL) with stirring. The solution was stirred at 40° C. for 0.5 h, poured into water (200 mL), extracted with Et2O (3×50 mL), washed with water (50 mL), dried (MgSO4) and the solvent removed under reduced pressure to give the title compound (2.35 g, 100%) as a brown oil.

1. stirringThe solution was stirred at 40° C. for 0.5 h
2. extractionextracted with Et2O (3×50 mL)
3. washwashed with water (50 mL)
4. dry with materialdried (MgSO4)
5. customthe solvent removed under reduced pressure