6-Aminohexanoic Acid → 6-Acrylamidohexanoic Acid

HRID 2369727Notes

Reaction equation

HRID 2369727 reaction equation
NCC(O)=O.[NH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13].[NH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24]>>[C:23]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])(=[O:24])[CH:22]=[CH2:21].[C:12]([NH:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24])(=[O:13])[CH:11]=[CH2:10]

Participants

5

Reactant 3

HCID 5646-Aminohexanoic AcidHCID 750GlycineHCID 660858-Aminooctanoic acid

Product 2

HCID 3242006-Acrylamidohexanoic AcidHCID 86194672HCID 86194672, compound

Procedure

N-acryloyl 2-glycine (A2AGA), N-acryloyl 4-aminobutyeric acid (A4ABA), N-acryloyl 6-aminocaproic acid (A6ACA) and N-acryloyl 8-aminocaprylic acid (A8ACA) were synthesized from glycine (Fisher Scientific Inc), 4-aminobutyeric acid, 6-aminocaproic acid and 8-aminocaprylic acid (Acros Organics Inc) respectively.

Sources & evidence

ORD record
ord-4775f4e131914e3ab5e6d40908f9cb7e
Source dataset
uspto-grants-2014_04
Patent number
US08709452B2

Reaction notes

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