HCID 57429416, compound → HCID 57429415, compound

Participants

Reaction Conditions

Reaction Steps

5% Pd/C (250 mg, 5% w/w) was charged into a 25 mL autoclave vessel with 3-(3-isopropylcyclohexyl)-2-methylenebutanal (4.5 g, 21.6 mmol) in methanol (5 mL). The mixture was vigorously stirred under an hydrogen atmosphere (10 Bar) at 40-45° C. for 40 minutes. The catalyst was filtered over celite and the solution was concentrated. The resulting crude product was distilled with a bulb-to-bulb distillation (2.5 mBar, 117° C.) to give 3-(3-isopropylcyclohexyl)-2-methylbutanal (3 g, gc purity>90%; yield=67%).

Provenance & Evidence