反应详情

To a stirred solution of 16.3 gm. (0.1 mole) of 5-nitroanthranilonitrile in 100 ml. of dry pyridine is added 18.56 gm. (0.1 mole) of p-nitrobenzoyl chloride. The reaction mixture is refluxed for three hours. The pyridine is distilled in vacuo. The oily residue is poured into 600 ml. of water and is distilled in vacuo. The oily residue is poured into 600 ml. of water and the precipitate removed by filtration. The precipitate is boiled with 1500 ml. of ethanol. The insoluble material is removed by filtration. There is obtained 21.57 gm. of yellow solid that melts at 195°-196°.

1. temperatureThe reaction mixture is refluxed for three hours
2. distillationThe pyridine is distilled in vacuo
3. additionThe oily residue is poured into 600 ml
4. distillationof water and is distilled in vacuo
5. additionThe oily residue is poured into 600 ml
6. customof water and the precipitate removed by filtration
7. customThe insoluble material is removed by filtration
8. customThere is obtained 21.57 gm