Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Thiophenecarboxaldehyde | HCID 7364 | — |
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | Dimethylamine, hydrochloride | HCID 10473 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 15190-02-0 | HCID 10702333 | — |
Reaction Steps
A solution of 131.5 g. of dimethylamine hydrochloride in 200 ml of water was stirred and 59 g of sodium cyanide added. A solution of 112 g of 2-thiophenecarboxaldehyde in 100 ml of methanol was added from a dropping funnel while the temperature was kept below 30° C. The mixture was then maintained at 30° C. for 4 hours; it was then poured into 3 1. of water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04159338 |
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| Source dataset | uspto-grants-1979_06 |
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| ORD ID | ord-3439f2dd7a824451877a12bef8280552 |
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| Source note | uspto-grants-1979_06 |
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