3-Nitrophenylethyl alcohol → 2-(3-Aminophenyl)ethan-1-ol

HRID 2370087Notes

Reaction equation

HRID 2370087 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[CH2:7][CH2:8][OH:9])([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([CH2:7][CH2:8][OH:9])[CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 1

HCID 1040583-Nitrophenylethyl alcohol

Product 1

HCID 149389872-(3-Aminophenyl)ethan-1-ol

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

3-Nitrophenethyl alcohol (5.80 g, 34.7 mmol) was dissolved in ethanol (80 mL), and 10% palladium on carbon (0.90 g) was added thereto, and then, the resulting mixture was stirred under a hydrogen atmosphere at room temperature for 1.5 hours.

Sources & evidence

ORD record
ord-e7b6df4908ee4c00ae72a02c679560dd
Source dataset
uspto-grants-2014_04
Patent number
US08710060B2

Reaction notes

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