Hydrochloric Acid → HCID 59226053, compound

Participants

Reaction Steps

425 mg of diastereomeric 1-amino-bicyclohexyl-4-ol (29) was synthesized as hydrochloride from 1.13 g (2.72 mmol) of 2-methyl-propane-2-sulfinic acid [4-(tert-butyl-dimethyl-silanyloxy)-bicyclohexyl-1-yl]-amide (27) following the procedure for 4-amino-4-cyclopropyl-cyclohexanol (28). Rt=0.61 min, 0.76 min (Method C). Detected mass: 198.3 (M+H+), 163.0 (M-NH3+H+).

Provenance & Evidence