HCID 21314899, compound → HCID 21314843, compound

HRID 237030Notes

Reaction equation

HRID 237030 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:13]2[CH2:18][CH2:17][N:16]([C:19]3[C:24]([F:25])=[CH:23][CH:22]=[CH:21][C:20]=3[F:26])[CH2:15][CH2:14]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-])=O>[Cl-].[Cl-].[Cl-].[Ti+3]>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:13]2[CH2:18][CH2:17][N:16]([C:19]3[C:20]([F:26])=[CH:21][CH:22]=[CH:23][C:24]=3[F:25])[CH2:15][CH2:14]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1

Participants

3

Reactant 1

HCID 21314899HCID 21314899, compound

Product 1

HCID 21314843HCID 21314843, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 5B, 1-[(p-nitrophenyl)sulfonyl]-4-(2,6-difluorophenyl)piperazine is reduced with titanium trichloride to give 1-[(p-aminophenyl)sulfonyl]-4-(2,6-difluorophenyl)piperazine.

Sources & evidence

ORD record
ord-1ead9a63b9b345e697d43c8729f3c219
Source dataset
uspto-grants-1979_06
Patent number
US04159331

Reaction notes

Loading…