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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2370305Generated: October 27, 2026

3-Bromo-4-fluorobenzaldehyde → 6-Fluoro-7-bromoisoquinoline

https://huagongshe.com/reaction/2370305

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-4-fluorobenzaldehydeHCID 173604—
Reactant6-FluoroisoquinolineHCID 21889847—
Product6-Fluoro-7-bromoisoquinolineHCID 53402964—

Reaction Steps

Starting from 3-bromo-4-fluoro-benzaldehyde, the title compound was prepared by the same reaction sequence as used for the synthesis of 6-fluoro-isoquinoline (3). Rt=0.91 min (Method B). Detected mass: 226.0 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08710077B2
Source datasetuspto-grants-2014_04
ORD IDord-fdecc21aa6c94b46b9d6801d886f85df
Source noteuspto-grants-2014_04