P-Anisidine → HCID 56943962, compound

HRID 2370440Notes

Reaction equation

HRID 2370440 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([OH:7])=O.[C:13](Cl)(=[O:16])[CH2:14][CH3:15].[CH3:18][O:19][C:20]1[CH:26]=[CH:25][C:23]([NH2:24])=[CH:22][CH:21]=1>>[CH3:18][O:19][C:20]1[CH:26]=[CH:25][C:23]([NH:24][C:5](=[O:7])[C:4]2[CH:8]=[CH:9][C:10]([O:11][CH3:12])=[C:2]([NH:1][C:13](=[O:16])[CH2:14][CH3:15])[CH:3]=2)=[CH:22][CH:21]=1

Participants

4

Reactant 3

HCID 7732P-AnisidineHCID 178233-Amino-4-methoxybenzoic acidHCID 62324Propionyl chloride

Product 1

HCID 56943962HCID 56943962, compound

Procedure

Compound 2611 is synthesized following a similar method as in Example 1 and using 3-amino-4-methoxybenzoic acid, propionyl chloride and 4-methoxyaniline as materials. Total yield of the two steps: 70%.

Sources & evidence

ORD record
ord-2bfb1e8717854e1cb16f33abcdf79044
Source dataset
uspto-grants-2014_04
Patent number
US08710098B2

Reaction notes

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