4-Nitroaniline → HCID 67320886, compound

HRID 2370450Notes

Reaction equation

HRID 2370450 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([OH:7])=O.[C:13](Cl)(=[O:16])[CH2:14][CH3:15].[N+:18]([C:21]1[CH:27]=[CH:26][C:24]([NH2:25])=[CH:23][CH:22]=1)([O-:20])=[O:19]>>[N+:18]([C:21]1[CH:27]=[CH:26][C:24]([NH:25][C:5](=[O:7])[C:4]2[CH:8]=[CH:9][C:10]([O:11][CH3:12])=[C:2]([NH:1][C:13](=[O:16])[CH2:14][CH3:15])[CH:3]=2)=[CH:23][CH:22]=1)([O-:20])=[O:19]

Participants

4

Reactant 3

HCID 74754-NitroanilineHCID 178233-Amino-4-methoxybenzoic acidHCID 62324Propionyl chloride

Product 1

HCID 67320886HCID 67320886, compound

Procedure

Compound 2612 is synthesized following a similar method as in Example 1 and using 3-amino-4-methoxybenzoic acid, propionyl chloride and 4-nitroaniline as materials. Total yield of the two steps: 53%.

Sources & evidence

ORD record
ord-a3b9db89879340d9b12afd328ae1d5e4
Source dataset
uspto-grants-2014_04
Patent number
US08710098B2

Reaction notes

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