3,4,5-Trimethoxyaniline → HCID 25256710, compound

HRID 2370452Notes

Reaction equation

HRID 2370452 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[C:6]([OH:8])=O)#[N:2].[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:20]=[C:21]([O:25][CH3:26])[C:22]=1[O:23][CH3:24])[NH2:19]>>[CH3:26][O:25][C:21]1[CH:20]=[C:18]([NH:19][C:6](=[O:8])[C:5]2[CH:9]=[CH:10][C:11]([O:12][CH3:13])=[C:3]([C:1]#[N:2])[CH:4]=2)[CH:17]=[C:16]([O:15][CH3:14])[C:22]=1[O:23][CH3:24]

Participants

3

Reactant 2

HCID 322853,4,5-TrimethoxyanilineHCID 219909723-Cyano-4-methoxybenzoic acid

Product 1

HCID 25256710HCID 25256710, compound

Procedure

Compound 68 is synthesized following a similar method as in Example 1 and using 3-cyano-4-methoxybenzoic acid and 3,4,5-trimethoxyaniline as materials. Total yield of the two steps: 60%.

Sources & evidence

ORD record
ord-0bae2557044c494490e21aa66e2c1d9b
Source dataset
uspto-grants-2014_04
Patent number
US08710098B2

Reaction notes

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