Aniline → 3-Amino-4-methoxybenzanilide

HRID 2370453Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([OH:7])=O.[NH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:7]

Participants

Reactant 2

HCID 6115Aniline

HCID 178233-Amino-4-methoxybenzoic acid

Product 1

HCID 84263-Amino-4-methoxybenzanilideYield 37%

Procedure

Using 3-amino-4-methoxybenzoic acid and aniline as materials, compound 2621 is synthesized following a similar method as in Example 28. Yield: 37%.

Sources & evidence

ORD record: ord-18d2b55997294f31b34e5e7bc1e0ff42
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08710098B2

Reaction notes

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