4-Amino-2-fluorobenzenesulfonamide → HCID 25255329, compound

HRID 2370454Notes

Reaction equation

HRID 2370454 reaction equation
[CH3:1][NH:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[C:6]([OH:8])=O.[F:14][C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][C:21]=1[S:22]([NH2:25])(=[O:24])=[O:23])[NH2:18]>>[F:14][C:15]1[CH:16]=[C:17]([NH:18][C:6](=[O:8])[C:5]2[CH:9]=[CH:10][C:11]([O:12][CH3:13])=[C:3]([NH:2][CH3:1])[CH:4]=2)[CH:19]=[CH:20][C:21]=1[S:22]([NH2:25])(=[O:24])=[O:23]

Participants

3

Reactant 2

HCID 223168984-Amino-2-fluorobenzenesulfonamideHCID 229768404-Methoxy-3-(methylamino)benzoic acid

Product 1

HCID 25255329HCID 25255329, compoundYield 52%

Procedure

Using 3-methylamino-4-methoxybenzoic acid and 3-fluoro-4-aminosulfonylaniline as materials, compound 98 is synthesized following a similar method as in Example 28. Yield: 52%.

Sources & evidence

ORD record
ord-d1903141ee2240129916c59a361cd793
Source dataset
uspto-grants-2014_04
Patent number
US08710098B2

Reaction notes

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