Isovanillic Acid → HCID 25255225, compound

HRID 2370458Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[C:5]([OH:7])=O.[CH3:13][O:14][C:15]1[CH:16]=[C:17]([CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23])[NH2:18]>>[CH3:25][O:24][C:20]1[CH:19]=[C:17]([NH:18][C:5](=[O:7])[C:4]2[CH:8]=[CH:9][C:10]([O:11][CH3:12])=[C:2]([OH:1])[CH:3]=2)[CH:16]=[C:15]([O:14][CH3:13])[C:21]=1[O:22][CH3:23]

Participants

Reactant 2

HCID 12575Isovanillic Acid

HCID 322853,4,5-Trimethoxyaniline

Product 1

HCID 25255225HCID 25255225, compoundYield 34%

Procedure

Using 3-hydroxyl-4-methoxybenzoic acid and 3,4,5-trimethoxyaniline as materials, compound 87 is synthesized following a similar method as in Example 28. Yield: 34%.

Sources & evidence

ORD record: ord-5e7a3b4a7712412a9aa29c2bd9e445ca
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08710098B2

Reaction notes

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