HCID 46944760, compound → HCID 46947541, compound

HRID 2370587Notes

Reaction equation

CC1(C)N(CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=[O:17])C(=O)N(C2C=CC([N+]([O-])=O)=C(C(F)(F)F)C=2)C1=O.[CH3:44][C:45]1([CH3:86])[N:49]([CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][S:60][CH2:61][CH2:62][CH2:63][C:64]([F:70])([F:69])[C:65]([F:68])([F:67])[F:66])[C:48](=[O:71])[N:47]([C:72]2[CH:77]=[CH:76][C:75]([N+:78]([O-:80])=[O:79])=[C:74]([C:81]([F:84])([F:83])[F:82])[CH:73]=2)[C:46]1=[O:85]>>[CH3:44][C:45]1([CH3:86])[N:49]([CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][S:60]([CH2:61][CH2:62][CH2:63][C:64]([F:69])([F:70])[C:65]([F:68])([F:67])[F:66])=[O:17])[C:48](=[O:71])[N:47]([C:72]2[CH:77]=[CH:76][C:75]([N+:78]([O-:80])=[O:79])=[C:74]([C:81]([F:83])([F:84])[F:82])[CH:73]=2)[C:46]1=[O:85]

Participants

Reactant 2

HCID 46944760HCID 46944760, compound

HCID 46947540HCID 46947540, compound

Product 1

HCID 46947541HCID 46947541, compoundYield 74%

Procedure

The experimental protocol used is the same as that described for the synthesis of the compound of Example 2, the compound of Example 8 replacing the compound of Example 1. The expected compound is obtained in the form of a pale yellow oil with a yield of 74% (71 mg).

Sources & evidence

ORD record: ord-b8c8b2ac93a542d69d67882e9da2e2f3
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08710091B2

Reaction notes

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