HCID 46944973, compound → HCID 46945366, compound

HRID 2370595Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[N:10]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][S:25][CH2:26][CH2:27][CH2:28][C:29]([F:35])([F:34])[C:30]([F:33])([F:32])[F:31])[C:9]2=[O:36])=[CH:4][C:3]=1[C:37](F)(F)F.CC1(C)N(CCCCCCCCCSCCCC(F)(F)C(F)(F)F)C(=O)N(C2C=CC([N+]([O-])=O)=C(C)C=2)C1=O>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[N:10]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][S:25][CH2:26][CH2:27][CH2:28][C:29]([F:35])([F:34])[C:30]([F:33])([F:31])[F:32])[C:9]2=[O:36])=[CH:4][C:3]=1[CH3:37]

Participants

Reactant 2

HCID 46944973HCID 46944973, compound

HCID 46945364HCID 46945364, compound

Product 1

HCID 46945366HCID 46945366, compoundYield 93%

Procedure

The experimental protocol is the same as that described for the compound of Example 16, the compound of Example 23 replacing the compound of Example 1. The expected compound is obtained in the form of a brown oil with a yield of 93%.

Sources & evidence

ORD record: ord-f75695261e524897aa549cd7b2004c31
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08710091B2

Reaction notes

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