HCID 46945366, compound → HCID 46945557, compound

HRID 2370598Notes

Reaction equation

[CH3:1][C:2]1([CH3:43])[N:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][S:16]([CH2:18][CH2:19][CH2:20][C:21]([F:27])([F:26])[C:22]([F:25])([F:24])[F:23])=[O:17])[C:5](=[O:28])[N:4]([C:29]2[CH:34]=[CH:33][C:32]([N+:35]([O-])=O)=[C:31]([C:38](F)(F)F)[CH:30]=2)[C:3]1=[O:42].NC1C=[CH:49][C:48]([N:51]2C(=O)C(C)(C)N(CCCCCCCCCSCCCC(F)(F)C(F)(F)F)[C:52]2=[O:79])=[CH:47][C:46]=1C>>[CH3:1][C:2]1([CH3:43])[C:3](=[O:42])[N:4]([C:29]2[CH:34]=[CH:33][C:32]([NH:35][C:52]([NH:51][CH:48]([CH3:49])[CH2:47][CH3:46])=[O:79])=[C:31]([CH3:38])[CH:30]=2)[C:5](=[O:28])[N:6]1[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][S:16]([CH2:18][CH2:19][CH2:20][C:21]([F:27])([F:26])[C:22]([F:23])([F:25])[F:24])=[O:17]

Participants

Reactant 2

HCID 46945366HCID 46945366, compound

HCID 46947540HCID 46947540, compound

Product 1

HCID 46945557HCID 46945557, compoundYield 63%

Procedure

The experimental protocol used is the same as that described for the synthesis of the compound of Example 2, the compound of Example 25 replacing the compound of Example 1. A colourless oil is obtained with a yield of 63%.

Workup

customA colourless oil is obtained with a yield of 63%

Sources & evidence

ORD record: ord-b4ac3c9c6dc544e99066d0aef92eeb44
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08710091B2

Reaction notes

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