HCID 46945559, compound → HCID 46945560, compound

HRID 2370601Notes

Reaction equation

[CH3:1][C:2]1([CH3:43])[N:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][S:16]([CH2:18][CH2:19][CH2:20][C:21]([F:27])([F:26])[C:22]([F:25])([F:24])[F:23])=[O:17])[C:5](=[O:28])[N:4]([C:29]2[CH:34]=[CH:33][C:32]([N+:35]([O-])=O)=[C:31]([C:38](F)(F)F)[CH:30]=2)[C:3]1=[O:42].CC1(C)C(=O)N(C2C=CC([NH:57][S:58](N)(=[O:60])=[O:59])=C(C)C=2)C(=O)N1CCCCCCCCCSCCCC(F)(F)C(F)(F)F>>[CH3:43][C:2]1([CH3:1])[C:3](=[O:42])[N:4]([C:29]2[CH:34]=[CH:33][C:32]([NH:35][S:58]([NH2:57])(=[O:60])=[O:59])=[C:31]([CH3:38])[CH:30]=2)[C:5](=[O:28])[N:6]1[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][S:16]([CH2:18][CH2:19][CH2:20][C:21]([F:27])([F:26])[C:22]([F:25])([F:23])[F:24])=[O:17]

Participants

Reactant 2

HCID 46945559HCID 46945559, compound

HCID 46947540HCID 46947540, compound

Product 1

HCID 46945560HCID 46945560, compoundYield 62%

Procedure

The experimental protocol used is the same as that described for the synthesis of the compound of Example 2, the compound of Example 30 replacing the compound of Example 1. A white solid is obtained with a yield of 62%.

Workup

customA white solid is obtained with a yield of 62%

Sources & evidence

ORD record: ord-b76ba4012bd64cd3887a479389cc0db3
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08710091B2

Reaction notes

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