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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2370721Generated: October 28, 2026

3-Chloro-4-fluorobenzaldehyde → 7-Chloro-6-fluoroisoquinoline

https://huagongshe.com/reaction/2370721

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-fluorobenzaldehydeHCID 593866—
Reactant6-FluoroisoquinolineHCID 21889847—
Product7-Chloro-6-fluoroisoquinolineHCID 53418922—

Reaction Steps

Starting from 3-chloro-4-fluoro-benzaldehyde, the title compound was prepared by the same reaction sequence as 6-fluoro-isoquinoline (5). Rt=0.77 min (Method #2). Detected mass: 182.1/184.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08710228B2
Source datasetuspto-grants-2014_04
ORD IDord-60b51efb322140ccaa4472855ecbfb97
Source noteuspto-grants-2014_04