HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoquinoline, 5-chloro-6-fluoro- → HCID 178454059, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoquinoline, 5-chloro-6-fluoro- | HCID 59818261 | — |
| Reactant | HCID 178418813 | HCID 178418813 | — |
| Product | HCID 178454059 | HCID 178454059 | — |
Reaction Steps
Starting from 5-chloro-6-fluoro-isoquinoline (8) and cis-(4-hydroxy-cyclohexyl)-carbamic acid tert-butyl ester the title compound was prepared by the method described for trans-[4-(5-chloro-isoquinolin-6-yloxy)-cyclohexyl]carbamic acid tert-butyl ester (10), whereas DMF was used as solvent. Rt=1.14 min (Method #4). Detected mass: 377.2/379.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710228B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-a3f0ff841f2a423495e14983eb2a88e8 |
| Source note | uspto-grants-2014_04 |