HCID 59268545, compound → HCID 59268525, compound

HRID 2370742Notes

Reaction equation

HRID 2370742 reaction equation
[CH3:1][O:2][CH:3]([O:16][CH3:17])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([F:13])[C:10]([F:14])=[C:9]([F:15])[CH:8]=1.COC(OC)CN(CC1C=CC(F)=CC=1)[S:23]([C:26]1[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=1)(=[O:25])=[O:24]>>[CH3:17][O:16][CH:3]([O:2][CH3:1])[CH2:4][N:5]([CH2:6][C:7]1[CH:8]=[C:9]([F:15])[C:10]([F:14])=[C:11]([F:13])[CH:12]=1)[S:23]([C:26]1[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=1)(=[O:25])=[O:24]

Participants

3

Reactant 2

HCID 59268545HCID 59268545, compoundHCID 59818264N-(2,2-Dimethoxy-ethyl)-N-(4-fluoro-benzyl)-4-methyl-benzenesulfonamide

Product 1

HCID 59268525HCID 59268525, compound

Procedure

Starting from (2,2-Dimethoxy-ethyl)-(3,4,5-trifluoro-benzyl)-amine (99), the title compound was prepared following the method described for N-(2,2-dimethoxy-ethyl)-N-(4-fluoro-benzyl)-4-methyl-benzene-sulfonamide (4). Rt=1.76 min (Method #4). Detected mass: 372.1 (M+H+).

Sources & evidence

ORD record
ord-50f80d08182f4a968ae8880b16759dac
Source dataset
uspto-grants-2014_04
Patent number
US08710228B2

Reaction notes

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