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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2370752Generated: October 25, 2026

Tert-Butanesulfinamide → (4-(Trifluoromethyl)phenyl)(3-(trifluoromethyl)pyridin-2-yl)methanamine Hydrochloride

https://huagongshe.com/reaction/2370752

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButanesulfinamideHCID 3382465—
Reactant(S)-(4-(Trifluoromethyl)phenyl)(3-(trifluoromethyl)pyridin-2-yl)methanamine HydrochlorideHCID 86687962—
Product(4-(Trifluoromethyl)phenyl)(3-(trifluoromethyl)pyridin-2-yl)methanamine HydrochlorideHCID 89310363—

Reaction Steps

Following the procedure detailed above for Intermediate 2, but replacing (S)-2-methylpropane-2-sulfinamide with racemic 2-methylpropane-2-sulfinamide in STEP 2 gave the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08710043B2
Source datasetuspto-grants-2014_04
ORD IDord-84188d0a739249749c8875fb196a34b6
Source noteuspto-grants-2014_04