HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphosgene → 2-Isopropylimino-3-benzyl-5-(p-methoxyphenyl)tetrahydro-1,3,5-thiadiazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphosgene | HCID 10426 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1,3,5-Triazine, hexahydro-1,3,5-tris(4-methoxyphenyl)- | HCID 11058579 | — |
| Reactant | N-Benzyl-N'-propan-2-ylthiourea | HCID 12725928 | — |
| Product | 2-Isopropylimino-3-benzyl-5-(p-methoxyphenyl)tetrahydro-1,3,5-thiadiazin-4-one | HCID 21314710 | 155.8% |
Reaction Steps
Similarly, 1.4 g (0.0033 mole) of 1,3,5-tris(p-methoxyphenyl)-hexahydro-s-triazine, 1 g (0.005 mole) of trichloromethyl chloroformate, 2.1 g (0.01 mole) of 1-isopropyl-3-benzylthiourea, and 9 ml of a 10% sodium hydroxide solution were used to obtain 1.9 g (52% yield) of 2-isopropylimino-3-benzyl-5-(p-methoxyphenyl)tetrahydro-1,3,5-thiadiazin-4-one (compound No. 356) of the formula, ##STR157## as white crystals melting at 114° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04159328 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-e0512e2674554e698bbf89c058329084 |
| Source note | uspto-grants-1979_06 |