HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphosgene → 2-Methylimino-3-methyl-5-(2,6-dimethylphenyl)-tetrahydro-1,3,5-thiadiazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphosgene | HCID 10426 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methanimine, N-(2,6-dimethylphenyl)- | HCID 141978 | — |
| Reactant | N,N'-Dimethylthiourea | HCID 2723631 | — |
| Product | 2-Methylimino-3-methyl-5-(2,6-dimethylphenyl)-tetrahydro-1,3,5-thiadiazin-4-one | HCID 21314731 | 22.5% |
Reaction Steps
Similarly, 2.7 g (0.02 mole) of N-methylene-2,6-dimethylaniline, 2.0 g of trichloromethyl chloroformate, 2.0 g (0.02 mole) of 1,3-dimethylthiourea, and 18 g of a 10% aqueous sodium hydroxide solution were used to obtain 0.6 g (12% yield) of 2-methylimino-3-methyl-5-(2,6-dimethylphenyl)-tetrahydro-1,3,5-thiadiazin-4-one (compound No. 389) of the formula, ##STR179## as a colorless oily substance (nD20 1.5967).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04159328 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-74934cae358f41c5998d8b14ae062304 |
| Source note | uspto-grants-1979_06 |