Hydrazine → 5-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazine

HRID 237092Notes

Reaction equation

HRID 237092 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10](SC)[N:11]=[N:12][CH:13]=1.[NH2:16][NH2:17]>CO.O1CCCC1>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10]([NH:16][NH2:17])[N:11]=[N:12][CH:13]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 125812725-(o-Fluorophenyl)-3-(methylthio)-1,2,4-triazine

Product 1

HCID 125812735-(o-Fluorophenyl)-3-hydrazino-1,2,4-triazine

Reagents, catalysts & solvents 1

HCID 21899815MeOH tetrahydrofuranSolvent

Procedure

To a solution of 27.6 g. of 5-(o-fluorophenyl)-3-(methylthio)-1,2,4-triazine in 100 ml. of 1:1 methanol-tetrahydrofuran is added 6.4 ml. of 95% hydrazine. The mixture is refluxed for about 22 hours and then cooled. The solid is recovered by filtration, giving 5-(o-fluorophenyl)-3-hydrazino-1,2,4-triazine as yellow crystals.

Workup

  1. temperatureThe mixture is refluxed for about 22 hours
  2. temperaturecooled
  3. filtrationThe solid is recovered by filtration

Sources & evidence

ORD record
ord-0e9a25fb1dbd49919dcb5386f49b5240
Source dataset
uspto-grants-1979_06
Patent number
US04159375

Reaction notes

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