Phenyl isocyanate → HCID 69331787, compound

Participants

Reaction Conditions

Reaction Steps

50 mg (0.10 mmol) of the compound from example 12f were dissolved in 10 ml of acetonitrile. The resulting solution was cooled to 0° C., and 14 mg (0.12 mmol, 13.2 μl) of phenyl isocyanate and 20 mg (0.20 mmol, 28 μl) of triethylamine were added. The mixture was warmed to RT, and a spatula tip of 4-dimethylaminopyridine was added. The reaction mixture was left to stand overnight and then evaporated, and the residue was chromatographed on silica gel. 47 mg of the title compound were obtained.

Provenance & Evidence