HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → 3-Chloro-6-(o-chlorophenyl)-1,2,4-triazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 6-(o-chlorophenyl)-1,2,4-triazin-3(2H)-one | HCID 12581287 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Chloro-6-(o-chlorophenyl)-1,2,4-triazine | HCID 12581288 | — |
Reaction Steps
A suspension of 53 g. of 6-(o-chlorophenyl)-1,2,4-triazin-3(2H)-one in 400 ml. of chloroform is cooled in an ice bath and 400 ml. of phosphorus oxychloride is added followed by 3 g. of N,N-dimethylformamide. The mixture is refluxed overnight and treated as described in Example 12, giving 3-chloro-6-(o-chlorophenyl)-1,2,4-triazine as white needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04159375 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-4e83232dfe3a455abe347a94cf3a2b3e |
| Source note | uspto-grants-1979_06 |