HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 11853395, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 69245421 | HCID 69245421 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11853395 | HCID 11853395 | 77.6% |
Reaction Steps
To a solution of the compound (120 mg) obtained from step 8 above in dichloromethane (5 ml) was added trifluoroacetic acid (2 ml) and stirred the reaction mixture for 2 hours at room temperature. The solvent was evaporated under reduced pressure and the residue thus obtained was purified by preparative thin layer chromatography (eluant: 60% ethyl acetate in hexane) to furnish the title compound (68 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710261B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-0a588f89edcc44df8d92143a52cc99de |
| Source note | uspto-grants-2014_04 |