Dimethylamine → HCID 53799959, compound

HRID 237128Notes

Reaction equation

HRID 237128 reaction equation
[Cl:1][C:2]1[CH:25]=[CH:24][CH:23]=[CH:22][C:3]=1[C:4]([C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[NH:13][N:14]=[C:15]([NH2:21])[C:16]([O:18]CC)=O)=[O:5].[CH3:26][NH:27][CH3:28]>CO>[Cl:1][C:2]1[CH:25]=[CH:24][CH:23]=[CH:22][C:3]=1[C:4]([C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[NH:13][N:14]=[C:15]([NH2:21])[C:16](=[O:18])[N:27]([CH3:28])[CH3:26])=[O:5]

Participants

4

Reactant 2

HCID 674DimethylamineHCID 53891769HCID 53891769, compound

Product 1

HCID 53799959HCID 53799959, compoundYield 85.5%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a suspension of 1-[2-(2-chlorobenzoyl)-4-chlorophenyl]-2-(1-amino-1-ethoxycarbonylmethylene)hydrazine (24.9 g) in methanol (300 ml), excess of gaseous dimethylamine is introduced at room temperature, and the reaction mixture is allowed to stand overnight. After evaporating the solvent under reduced pressure, the residue is recrystallized from ethanol to give 1-[2-(2-chlorobenzoyl)-4-chlorophenyl]-2-(1-amino-1-dimethylcarbamoylmethylene)hydrazine (21.3 g) as reddish orange crystals melting at 150 to 151° C. The yield is 85.5%.

Workup

  1. customAfter evaporating the solvent under reduced pressure
  2. customthe residue is recrystallized from ethanol

Sources & evidence

ORD record
ord-c20fb0785a284f5fa2e6112d1520e17a
Source dataset
uspto-grants-1979_06
Patent number
US04159374

Reaction notes

Loading…