HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (R)-3-Allylsulfanyl-2-amino-propionic acid methyl ester hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (R)-3-Allylsulfanyl-2-tert-butoxycarbonylamino-propionic acid methyl ester | HCID 86650241 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (R)-3-Allylsulfanyl-2-amino-propionic acid methyl ester hydrochloride | HCID 86650242 | — |
Reaction Steps
Methyl ester 29 (3.20 g, 11.6 mmol) was dissolved in 4M hydrogen chloride in 1,4-dioxane (40 mL). The resultant solution was stirred at rt for 18 h before being concentrated in vacuo to yield a white solid, 2.46 g, 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710178B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-d7a93993265f436cb5f9f87213894c36 |
| Source note | uspto-grants-2014_04 |