Phthalic Anhydride → HCID 19907327, compound

HRID 2371436Notes

Reaction equation

HRID 2371436 reaction equation
[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[F:12][C:13]1[CH:14]=[C:15]([NH2:22])[C:16](=[CH:20][CH:21]=1)[C:17]([OH:19])=[O:18]>ClCCl>[C:4]([C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[C:1]([NH:22][C:15]1[C:16](=[CH:20][CH:21]=[C:13]([F:12])[CH:14]=1)[C:17]([OH:19])=[O:18])=[O:11])([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 6811Phthalic AnhydrideHCID 27249674-Fluoroanthranilic acid

Product 1

HCID 19907327HCID 19907327, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of phthalic anhydride (4.8 g) and 4-fluoroanthranilic acid (5 g) in dichloromethane (100 ml) was stirred at room temperature for 48 hours and the solid collected and washed with dichloromethane to give N-(2-carboxybenzoyl)-4-fluoroanthranilic acid, m.p. 187°-188°. (Compound 1).

Workup

  1. customthe solid collected
  2. washwashed with dichloromethane

Sources & evidence

ORD record
ord-e327f3ccf6994df08d94d0c501aa15c9
Source dataset
uspto-grants-1992_03
Patent number
US05093364

Reaction notes

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