HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 19907336, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(Trimethylsilyl)ethanol | HCID 18013 | — |
| Reactant | 7-Fluoroisatoic anhydride | HCID 10058138 | — |
| Solvent | Diisopropyl Ether | HCID 7914 | — |
| Product | HCID 19907336 | HCID 19907336 | — |
Reaction Steps
7-Fluoro-1H-3,1-benzoxazine-2,4-dione (2.0 g), sodium hydroxide (0.05 g) and 2-(trimethylsilyl)ethanol (1.31 g) were heated together at 100° for 30 minutes until effervescence ceased. After cooling, the residue was suspended in diisopropyl ether, then filtered and evaporated. The residue was recrystallised from petroleum ether to give 2-(trimethylsilyl)ethyl 4-fluoroanthranilate, mp 43°-44°. (Compound 20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05093364 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-e8c7d98d6a2e4adcaa4b3eff9f08eac1 |
| Source note | uspto-grants-1992_03 |