反应详情

A mixture of 400 g triethylene glycol monoethyl ether (2.2 mol), 48 g paraformaldehyde (1.6 mol), 150 ml toluene and 10 g of an acid ion exchange resin was refluxed for 6 hours in a 1 liter flask equipped with a water separator and reflux condenser. Filtration of the product followed by distillation gave a quantitative yield of the desired product.

1. temperaturewas refluxed for 6 hours in a 1 liter flask
2. temperaturereflux condenser
3. filtrationFiltration of the product
4. distillationfollowed by distillation