Nitric Acid → HCID 19907403, compound

Participants

Reaction Steps

To 1 ml of 60% nitric acid was added 1 ml of 97% sulfuric acid under ice-cooling, and the mixture was stirred for 10 minutes. After adding 0.42 g of 1,4-bis(4-bromobutyl)benzene, the whole was stirred at a room temperature for an hour. The reaction mixture was poured onto ice, and extracted with total 60 ml of chloroform. The extract was washed with a saturated sodium chloride aqueous solution, dried over magnesium sulfate and evaporated under a reduced pressure to remove the solvent. The residue was applied to a silica gel column and eluted with chloroform/hexane (1:1). From the first fraction, 0.43 g of the title compound was obtained as a pale yellow liquid.

Provenance & Evidence