HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Benzene, (2-chloroethoxy)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Phenoxyethanol | HCID 31236 | — |
| Catalyst | Benzyltrimethylammonium chloride | HCID 5963 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Benzene, (2-chloroethoxy)- | HCID 12156 | — |
Reaction Steps
2-phenoxy-ethanol is reacted with thionyl chloride in the presence of benzyl-trimethyl ammonium chloride in a weight ratio of alcohol to tetra-alkyl-ammonium chloride of 28:1 respectively, in dichloromethane as a solvent, at a temp. of from about 10° C. to 50° C. to form 2-phenoxy ethyl chloride;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05093526 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-bdf42399b93644b39daacecd070c8a6f |
| Source note | uspto-grants-1992_03 |