Potassium Iodide → HCID 14697337, compound

Participants

Reaction Steps

10 g (40 mmol) of 1-chloro-8-tolyloctane, 21.2 g (120 mmol) of 4-hydroxy-4-phenylpiperidine, 5.52 g (40 mmol) of potassium carbonate and 3.3 g (20 mmol) of potassium iodide are heated with 30 ml of xylene at 160° C. for 8 h. The solvent is removed by distillation under reduced pressure. The residue is taken up in dichloromethane/dilute sodium hydroxide solution, and the organic extract is worked up in a conventional manner. The low-boiling compounds are removed by distillation under reduced pressure up to 150° C./0.9 mbar. 11.4 g (94%) of a resin are obtained (see Tab. 1 for physical data).

Provenance & Evidence