HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Isocyanate → Fluzinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 3-[3-(Trifluoromethyl)phenoxy]azetidine | HCID 11138538 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Fluzinamide | HCID 53467 | — |
Reaction Steps
To 6.0 g (0.024 mole) of 3-[3-(trifluoromethyl)phenoxy]azetidine in 50 ml of dry benzene was added dropwise 1.37 g (0.024 mole) of methylisocyanate, and stirring was continued for 30 minutes. The solid which crystallized in the flask was recrystallized from 95% ethanol to obtain 5.0 g (76%), mp 145°-147°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05095014 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-c0e6e33b631d47dda396ad254f5a5c50 |
| Source note | uspto-grants-1992_03 |